Showing posts with label Cancer. Show all posts
Showing posts with label Cancer. Show all posts

Wednesday, March 25, 2015

Powerful Antioxidant of Olive Oil Able to Kill Cancer Cells in Hours

""The major antioxidant compound found in olive oil is capable of killing cancer cells in less than an hour while leaving healthy cells unharmed, according to a study conducted by researchers from Rutgers University and Hunter College and published in the journal Molecular & Cellular Oncology.

The researchers hope that this may lead to a targeted cancer therapy based on this molecule.

"The Mediterranean diet is known to be associated with a reduced risk of many different kinds of cancer," researcher Paul Breslin said. "Whereas the entire diet likely has many benefits, this study points directly to the olive oil phenolic, oleocanthal, as playing an especially important role in these observations. As more people turn to the Mediterranean diet as a healthy life option, oleocanthal is growing in its significance as a key active component of this diet."



Makes "all hell break loose" for cancer

Many healthful plant compounds are known to induce apoptosis, or programmed cell death, in cancer cells by targeting a specific protein that controls the process. Yet apoptosis typically takes between 16 and 24 hours to complete, and prior studies had shown that cancer cells exposed to oleocanthal died within 30 to 60 minutes of exposure. The oleocanthal was acting much too fast, suggesting some mechanism other than apoptosis.

"We needed to determine if oleocanthal was targeting that protein and causing the cells to die," Breslin said.

In the new study, the researchers discovered that oleocanthal was indeed killing cancer cells by a different mechanism. Rather than targeting the apoptosis protein, oleocanthal was breaking apart the lysosomes of cancer cells. These organelles are responsible for processing cellular waste, and are much larger and more fragile in cancer cells than in healthy cells.

"Once you open one of those things, all hell breaks loose," Breslin said.

The study showed that once the lysosomes burst apart, critical life-sustaining functions in the cancer cells began to break down.

Significantly, oleocanthal did not harm nearby healthy cells. Instead, it put them into a kind of stasis or hibernation for about a day. After that time, the cells resumed normal, healthy functioning with no apparent lasting effects.

"The mechanism of killing cancer cells and sparing healthy cells, lysosomal membrane permeabilization, has been hypothesized as a possible mechanism of effectively killing cancer cells and sparing healthy tissues but has never been realized before," Breslin said. "Our realization of this makes this paper of particular therapeutic interest for cancer treatment."
It will still be many years, however, before an oleocanthal treatment could become available. That's because complete organisms are much more complex than cell cultures, and the olive oil compound may act differently in the human body.""



Friday, January 16, 2015

Wifi RF Exposure "Appears" Greater Danger to Children's Developmental Health than to Adult's Well-being

""Forbes writer Robert J. Szczerba states he simply wants to apply common sense rules to a technology that has been -- in his view -- overlooked by manufacturers.
Manufacturers like Apple do extensively test and list detailed information about RF signals on their website - in the case of the iPhone 6 this information recommends you carry your device 5mm away from your body to maintain safe standards (1.6 watts per kilogram) as required by law in many countries.
The effects of RF and WiFi signals on adults and children have been extensively looked at elsewhere.
In the UK an independent advisory group on non-ionising radiation, headed by Professor AJ Swerdlow, produced a detailed report on RF that said there was no evidence that demonstrated "any adverse health effects of RF field exposure below internationally accepted guideline levels".
It also said that "there is increasing evidence that RF field exposure below guideline levels does not cause symptoms and cannot be detected by people, even by those who consider themselves to be sensitive to RF fields".
That review also looked at studies into RF exposure in children - particularly as it related to reaction time, rather than cancer or other illness.
It said that one 2004 study which exposed 32 children aged 10-14 in a double-blind test found no significant effects of exposure. Another 2005 study found no significant results in a similar experiment.
The report did say that "caution is needed in interpreting the effect of exposure on simple reaction time, particularly since the effect replicates those observed in earlier studies of adults".
But it also concluded that "there is no convincing evidence that RF field exposure below guideline levels causes health effects in adults or children".
Forbes notes that the study it quotes tries to link RF exposure to cancer but admits it takes 30 years on average for a tumor to develop - meaning a link (if one exists) is difficult to prove.""
Click Here to Read Beginning of Report:

Bioscientists Create Tumor Extracting NanoVelcro Chip to Purify Diseased Blood Cells

""An international group led by scientists at UCLA’s California NanoSystems Institute has developed a new method for effectively extracting and analyzing cancer cells circulating in patients’ blood.
Circulating tumor cells are cancer cells that break away from tumors and travel in the blood, looking for places in the body to start growing new tumors called metastases. Capturing these rare cells would allow doctors to detect and analyze the cancer so they could tailor treatment for individual patients.
In his laboratory at the UCLA California NanoSystems Institute, Hsian-Rong Tseng, a professor of molecular and medical pharmacology, used a device he invented to capture circulating tumor cells from blood samples.
The device, called the NanoVelcro Chip, is a postage-stamp–sized chip with nanowires that are 1,000 times thinner than a human hair and are coated with antibodies that recognize circulating tumor cells. When 2 milliliters of blood are run through the chip, the tumor cells stick to the nanowires like Velcro.
Capturing the tumor cells was just part of the battle, though. To analyze them, Tseng’s team needed to be able to separate the cells from the chip without damaging them.""

Read Second Half Here:

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